Ameloblastic fibroma: a series of 10 cases from South America

José Alcides Almeida  de Arruda; José Victor Lemos Ventura; Maria Eduarda Zeraik Barreto; Mariana Villarroel-Dorrego; Claudia Patricia Peña-Vega; Juan Pablo Rodríguez-Mora; Ana Carolina Velasco Pondé de Sena; Israel Leal Cavalcante; Isabella Bittencourt do Valle; Emanuel Sávio de Souza Andrade; Gerhilde Callou Sampaio; Jefferson R. Tenório; Bruno Augusto Benevenuto de Andrade

doi:10.5327/2525-5711.287

Authors

José Alcides Almeida de Arruda Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-6599-3950
José Victor Lemos Ventura Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0009-0004-5719-2565
Maria Eduarda Zeraik Barreto Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-9009-5757
Mariana Villarroel-Dorrego Universidad Central de Venezuela, School of Dentistry – Caracas, Venezuela. https://orcid.org/0000-0002-0596-1527
Claudia Patricia Peña-Vega Universidad Nacional de Colombia, School of Dentistry, Service of Oral and Maxillofacial Pathology – Bogotá, Colombia. https://orcid.org/0000-0002-4532-3642
Juan Pablo Rodríguez-Mora Universidad Nacional de Colombia, School of Dentistry, Service of Oral and Maxillofacial Pathology – Bogotá, Colombia. https://orcid.org/0009-0009-3198-1861
Ana Carolina Velasco Pondé de Sena Universidade Federal da Bahia, School of Dentistry, Postgraduate Program in Dentistry and Health – Salvador (BA), Brazil. https://orcid.org/0000-0003-1083-9064
Israel Leal Cavalcante Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-0794-4106
Isabella Bittencourt do Valle Universidade Federal do Espírito Santo, Department of Pathology – Vitória (ES), Brazil. https://orcid.org/0000-0002-3221-3057
Emanuel Sávio de Souza Andrade Universidade de Pernambuco, School of Dentistry, Department of Oral and Maxillofacial Surgery and Pathology – Recife (PE), Brazil. https://orcid.org/0000-0003-2165-4217
Gerhilde Callou Sampaio Universidade de Pernambuco, School of Dentistry, Department of Oral and Maxillofacial Surgery and Pathology – Recife (PE), Brazil. https://orcid.org/0000-0001-8437-471X
Jefferson R. Tenório Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-6986-9148
Bruno Augusto Benevenuto de Andrade Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-3259-606X

DOI:

https://doi.org/10.5327/2525-5711.287

Keywords:

Jaws, Odontogenic tumors, Oral diagnosis, Oral medicine, Oral pathology

Abstract

Objective: Ameloblastic fibroma (AF) is a rare odontogenic tumor composed of ectomesenchymal tissue and epithelial components, without the formation of dental hard tissues. Despite its recognition, data on AF from South America remain limited. This study describes a series of 10 AF cases from Venezuela and Colombia.

Methods: Clinicopathological data, radiographic characteristics, and treatment modalities were analyzed descriptively.

Results: The series comprised seven (70%) female and three (30%) male patients, with a mean age of 12.9 years. Lesions were predominantly located in the posterior mandible (80%). Radiographic findings revealed radiolucent lesions associated with bone expansion and involvement of adjacent teeth. Treatment modalities included mandibular resection and hemimandibulectomy, accounting for 66.6% of cases. Recurrence was observed in one case (16.7%).

Conclusion: This study provides novel data on AF in South America, particularly in pediatric patients, and highlights the need for long-term surveillance and optimized treatment strategies due to the potential for recurrence.

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