Solitary fibrous tumor of the upper lip: an uncommon case presentation

Hélder Antônio Rebelo  Pontes; Carina Barros do Amaral; Esther Castro de  Menezes; Igor Mesquita  Lameira; Nathalia Rodrigues Gomes; Nicolau Conte  Neto; Rosa Hiolanda Abreu de Sousa; Sue Ann Lavareda Correa  Uchoa; Tatiana Ferreira Foscaldo; Flávia Sirotheau Correa  Pontes

doi:10.5327/2525-5711.309

Authors

Hélder Antônio Rebelo Pontes Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0002-7609-8804
Carina Barros do Amaral Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0009-0000-3601-3848
Esther Castro de Menezes Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0002-8935-3659
Igor Mesquita Lameira Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0003-3776-201X
Nathalia Rodrigues Gomes Federal University of Minas Gerais, School of Dentistry, Department of Oral Surgery and Pathology – Belo Horizonte (MG), Brazil. https://orcid.org/0000-0003-4198-3042
Nicolau Conte Neto Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0001-5152-1277
Rosa Hiolanda Abreu de Sousa Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0002-9494-8892
Sue Ann Lavareda Correa Uchoa Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0002-1913-9606
Tatiana Ferreira Foscaldo Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0002-1913-9606
Flávia Sirotheau Correa Pontes Federal University of Para, João de Barros Barreto University Hospital, Service of Oral Pathology – Belém (PA), Brazil. https://orcid.org/0000-0001-9125-6631

DOI:

https://doi.org/10.5327/2525-5711.309

Keywords:

Solitary Fibrous Tumor, Immunohistochemistry, Diagnosis, Lip

Abstract

Solitary Fibrous Tumor (SFT) is a rare mesenchymal neoplasm, account approximately 3% of mesenchymal tumors in the oral cavity. We present the case of a 65-year-old female patient with a painless swelling in the left upper lip. Clinical examination revealed a firm, smooth-surfaced submucosal lesion without ulceration, non-tender on palpation, and exhibiting a slightly yellowish hue. Computed tomography demonstrated a well-defined, isodense mass measuring 25 mm in diameter, with no evidence of bone invasion. The lesion was surgically excised, and histopathological analysis confirmed the diagnosis of SFT, supported by positive immunohistochemical staining for CD34 and STAT6. The tumor was classified as low risk for metastasis, and the patient demonstrated favorable postoperative recovery. The patient remains under follow-up with the medical team and has been recurrence-free for 07 months. This case underscores the rarity of oral cavity SFT and emphasizes the importance of comprehensive differential diagnosis to guide effective management and reduce recurrence risk.

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