Calcifying epithelial odontogenic tumor: a case series from South America

José Alcides Almeida de Arruda; José Victor Lemos Ventura; Maria Eduarda Zeraik Barreto; Mariana Villarroel-Dorrego; Claudia Patricia Peña-Vega; Juan Pablo Rodríguez-Mora; Alejandra Rojas-Ponte; Israel Leal Cavalcante; José Ricardo Dias Pereira; Gerhilde Callou Sampaio; Isabella Bittencourt do  Valle; Kallana Mezzomo Faccin; Ricardo Luiz Cavalcanti de Albuquerque-Junior; Rogério Gondak; Jefferson Rocha Tenório; Bruno Augusto Benevenuto de Andrade

doi:10.5327/2525-5711.286

Autores

José Alcides Almeida de Arruda Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-6599-3950
José Victor Lemos Ventura Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0009-0004-5719-2565
Maria Eduarda Zeraik Barreto Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-9009-5757
Mariana Villarroel-Dorrego Universidad Central de Venezuela, School of Dentistry – Caracas, Venezuela. https://orcid.org/0000-0002-0596-1527
Claudia Patricia Peña-Vega Universidad Nacional de Colombia, School of Dentistry, Service of Oral and Maxillofacial Pathology – Bogotá, Colombia. https://orcid.org/0000-0002-4532-3642
Juan Pablo Rodríguez-Mora Universidad Nacional de Colombia, School of Dentistry, Service of Oral and Maxillofacial Pathology – Bogotá, Colombia. https://orcid.org/0009-0009-3198-1861
Alejandra Rojas-Ponte Sanitas-Keralty, Servicio de Cirugía Oral y Maxilofacial – Bogotá, Colombia. https://orcid.org/0000-0003-1811-5220
Israel Leal Cavalcante Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-0794-4106
José Ricardo Dias Pereira Universidade de Pernambuco, School of Dentistry, Department of Oral and Maxillofacial Surgery and Pathology – Recife (PE), Brazil. https://orcid.org/0009-0007-7244-7628
Gerhilde Callou Sampaio Universidade de Pernambuco, School of Dentistry, Department of Oral and Maxillofacial Surgery and Pathology – Recife (PE), Brazil. https://orcid.org/0000-0001-8437-471X
Isabella Bittencourt do Valle Universidade Federal do Espírito Santo, Department of Pathology – Vitória (ES), Brazil. https://orcid.org/0000-0002-3221-3057
Kallana Mezzomo Faccin Universidade Federal de Santa Catarina, Division of Oral Diagnosis, Postgraduate Program in Dentistry – Florianópolis (SC), Brazil. https://orcid.org/0009-0000-9073-3301
Ricardo Luiz Cavalcanti de Albuquerque-Junior Universidade Federal de Santa Catarina, Health Sciences Center, Department of Pathology – Florianópolis (SC), Brazil. https://orcid.org/0000-0003-4444-7632
Rogério Gondak Universidade Federal de Santa Catarina, Health Sciences Center, Department of Pathology – Florianópolis (SC), Brazil. https://orcid.org/0000-0001-7547-660X
Jefferson Rocha Tenório Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-6986-9148
Bruno Augusto Benevenuto de Andrade Universidade Federal do Rio de Janeiro, School of Dentistry, Department of Oral Diagnosis and Pathology – Rio de Janeiro (RJ), Brazil. https://orcid.org/0000-0002-3259-606X

DOI:

https://doi.org/10.5327/2525-5711.286

Palavras-chave:

Jaws, Odontogenic tumors, Oral diagnosis, Oral medicine, Oral pathology

Resumo

Objective: To describe a case series of calcifying epithelial odontogenic tumor (CEOT) from South America.

Methods: This study analyzed cases from Brazil (n=7), Venezuela (n=4), and Colombia (n=1), providing their clinicopathologic, radiographic, and treatment characteristics.

Results: The series comprised seven (58.3%) females and five (41.7%) males, with a mean age at diagnosis of 33.4 years (range: 19–61). Clinically, 66.7% of patients presented with swelling, and the duration of the lesions ranged from 24 to 120 months. The mandible was involved in 91.7% (n=11) of cases, predominantly in the posterior region (83.4%). Radiographically, 83.4% of lesions were expansive, 75% displayed mixed density, 58.4% were associated with an impacted tooth, and 50% showed root resorption. The median lesion size was 45 mm. Histopathologically, 10 (83.3%) cases were classified as “classic” CEOT, while two (16.7%) were identified as the clear-cell variant. Curettage was performed in 50% of cases and surgical removal (en bloc) in 33.3%. No recurrences were observed in nine (81.8%) cases over a median follow-up of 36 months. Conclusion: These findings align with existing literature, highlighting a predominance of young adult females who often present with asymptomatic swelling. The importance of vigilant long-term follow-up post-treatment is emphasized.

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